The National Institutes of Health awarded the Cincinnati Children’s Hospital Medical Center a $12 million grant to identify which Migraine prevention medications work best for children and teens. The University of Iowa was given a $5.8 million grant to act as the data coordinating center for this study as well.
Dr. Andrew Hershey and Scott Powers, co-directors of the Headache Center at Cincinnati Children's Hospital, will be leading the five-year, 40 state clinical study. The study will include 675 participants between 8-17 years of age, comparing the use of amitriptyline and topiramate.
There is currently no Migraine prevention medication approved by the FDA for children and teens to take, but amitriptyline and topiramate are sometimes used to treat children and teens with Migraine. However, there are few studies on their effectiveness. While potential unwanted side effects can occur with both medications, the benefits of taking the medication may outweigh the risks due to the debilitating nature of Migraine. "Children and teens miss more than 130,000 school days every two weeks due to migraines," Hershey said recently. "The negative impact of having migraines on overall quality of life is similar to childhood cancer, heart disease and rheumatic disease," Powers said.
“The results of this trial will change current clinical practice by ensuring that decisions on early, effective treatment for millions of children and adolescents with migraine can now be based upon sound evidence,” Powers said.
This is exciting news for children and teens and will certainly bring more awareness to Migraine disease. Thank you NIH!
Glenn, Brendon. MedCity/Cleveland. "Cininnati Children's gets $12 M NIH grant for migraine clinical trials." September 28, 2011.
WLWT. Channel 5. Health."Children's Hospital Gets $12 Million To Study Migraines. Hospital to Lead 40 Sites in Research."
Thanks for reading and feel well,
© Nancy Harris Bonk, 2011.Last updated September 29, 2011.